Glycosyltransferase Function in Core 2-Type Protein O Glycosylation

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Glycosyltransferase function in core 2-type protein O glycosylation.

Three glycosyltransferases have been identified in mammals that can initiate core 2 protein O glycosylation. Core 2 O-glycans are abundant among glycoproteins but, to date, few functions for these structures have been identified. To investigate the biological roles of core 2 O-glycans, we produced and characterized mice deficient in one or more of the three known glycosyltransferases that gener...

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ژورنال

عنوان ژورنال: Molecular and Cellular Biology

سال: 2009

ISSN: 0270-7306,1098-5549

DOI: 10.1128/mcb.00204-09